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Welcome to Florida State University's official entrepreneurship and innovation podcast, The InNOLEvation® Mindset! Hosted by Mark McNees and powered by the Jim Moran College of Entrepreneurship. This podcast features audio and video versions of our podcast, which highlights student and alumni entrepreneurs and innovators from FSU.
Get inspired by the next generation of young business leaders and hear their inside stories. Learn from faculty who teach entrepreneurship and innovation courses at FSU as they share key insights.
On this channel, you'll find:
-Full video episodes of our podcast conversations with founders of startups born at FSU
-Business advice and thought leadership from FSU professors focused on entrepreneurship
-Fireside chats and interviews recorded live with enterprising alumni making their mark
-Special segments and speaker events at FSU focused on innovation
Whether you're an aspiring entrepreneur, a current business owner, or you just love hearing success stories - subscribe now to see inspiring individuals daring to turn ideas into reality. With new episodic content added regularly, The Innovation Mindset podcast tells tales of vision, grit, failure, and triumph straight from the FSU community.
This channel visually brings the podcast to life with photos, graphics, and video. Join us by subscribing if you bleed garnet and gold!
Episodes

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49 min
Host Mark McNees welcomes back Ava Polly (CCO) and Zachary Asarnow (CEO) of Esperance Biotech to discuss their progress since first appearing on the InNOLEvation® Mindset Podcast. They recap traveling to Paris for iGEM and iGEM Startups, joining residencies in Vienna and San Francisco, and graduating from FSU, while noting co-founder Eli continues lab work. Esperance is developing a genetically engineered probiotic to treat trimethylaminuria (TMAU), a rare genetic disease that causes a rotting-fish odor and severe social and psychological harm, and they see broader applications, including cardiovascular disease. They describe iterating on their design, early in vitro results showing a reduction in TMA by over 98% in two hours, plans for gut simulation and animal testing, and pursuing an FDA orphan drug pathway after pivoting away from a supplement route. They also discuss incubator benefits, networking, time prioritization, and the advice they’d give their earlier selves.
Contact Info
email is staff@esperance.bio
website is esperance.bio

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